New adenovirus induces response

Nature Reviews Clinical Oncology 7, 422 (2010). doi:10.1038/nrclinonc.2010.109

Author: Lisa Hutchinson
The antitumor efficacy of oncolytic viruses can be influenced by the immune system. Adenoviruses are among the most advanced cancer gene therapy approaches; however, despite evidence of activity of these agents in clinical trials, single-agent efficacy has been disappointing. Researchers from Helsinki generated an oncolytic (Source: Nature Clinical Practice Oncology)