Very Early Life Influences Later Life
One of the predictions of reliability theory as applied to aging is that we are all born with an existing level of damage. One of the ways in which that damage might occur - and "damage" here is a Continue Reading
Research and Clinical Development Industries in the US Must Start to Extend Beyond the US
If research and development in medicine is to move at anywhere near the pace it is capable of, given the rapid progress in all forms of underlying biotechnology, it must find a way to extend beyond Continue Reading
Tracking the Onset of Type 2 Diabetes
Type 2 diabetes (T2D) is a lifestyle disease for the vast majority of people - you avoid it by refraining from overeating, becoming fat, and giving up exercise to turn sedentary. But some folk are Continue Reading
Alzheimer’s Starts Early
The onset of Alzheimer's is not a sudden thing, which reinforces the view of it as a lifestyle disease: "The first changes in the brain of a person with Alzheimer's disease can be observed as much as Continue Reading
Development of Exercise Mimetics Will Recapitulate the Development of Calorie Restriction Mimetics
Exercise mimetics are drugs that can replicate some fraction of the beneficial effects of exercise; their development is in the early stages. I don't think it's too far-fetched to suggest that the Continue Reading
Towards Limb Regrowth in Mammals
From Big Think: "The loss of a human limb is a tragedy. We know that once they're gone, mammalian arms and legs can't ever be restored. But if you cut off a salamander's leg - or tail - it will Continue Reading
Supercentenarian Genomes Sequenced
Two supercentenarian genomes have been sequenced, and suggest that - as always - the roots of variations in human longevity are more complex than we'd like them to be: "Supercentenarians (age 110+ Continue Reading
Reversing Artificially Accelerated Aging is Not Interesting
The popular press will give just as much attention to an advance that extends life in healthy laboratory animals as they will to a technology demonstration that even partially reverses an Continue Reading
Feed Your Face: Younger, Smoother Skin and a Beautiful Body in 28 Delicious Days
Feed Your Face: Younger, Smoother Skin and a Beautiful Body in 28 Delicious Days is crammed full of interesting facts and figures and it is all presented in a “sound bite” fashion with Continue Reading
A Look Back at 2011
It has been an interesting year, and I suppose it is traditional at the tail end of December to cast a thoughtful eye back at the highlights. Which I will do, and the following items are in no Continue Reading
Thoughts on the Immune System and Aging
In aging there is a lot of correlation - many biological systems that are traditionally studied separately are declining at once, so most researchers are only looking in detail at one tiny part of Continue Reading
Obesity, Aging, Fat Tissue, and Telomeres
Pulling together the connections in a review paper: "Obesity is a condition in which excess or abnormal fat accumulation may present with adverse effects on health and decreased life expectancy. Continue Reading
When You Make Medical Progress Illegal, What Results is a Black Market in Medical Progress
I note a symptom of the highly restrictive FDA regulations on development of clinical therapies: The indictment alleges the four distributed stem cells and other biological products without federal Continue Reading
Commentary on the Naked Mole Rat Genome
A commentary at the journal Aging: "In the past 15 years, genomics has penetrated all areas of the life sciences, and this dramatic change in the way science is done is often viewed as genome Continue Reading
Increased Longevity Versus Reduced Reproduction in Humans?
Human studies may reveal a correlation between longevity and lower rates of reproduction: "A number of leading theories of aging, namely The Antagonistic Pleiotropy Theory (Williams, 1957), The Continue Reading
Needed: a Robust Way of Identifying Senescent Cells
This year saw a demonstration showing noteworthy benefits to health and longevity from the targeted destruction of senescent cells in mice - an expected result for many researchers, but one that had Continue Reading
Thoughts on the Longevity of Birds
A recent paper: "Birds generally age slower and live longer than similar sized mammals. For birds this occurs despite elevated blood glucose levels that for mammals would in part define them as Continue Reading
Oxidative Stress and Gender Longevity Differences
Here is another of the many theories aiming to explain why women live longer than men: "One of the most significant achievements of the twentieth century is the increase in human lifespan. In any Continue Reading
Methuselah Foundation Sneak Peek and Call for Donations
So what is the Methuselah Foundation up to these days? As you might know, the Foundation has administered the Mprize for longevity science since 2003: a multi-million dollar prize fund that Continue Reading
PAINLESS CAVITIES? NEW Plasma brush on the horizon
After favorable lab results, University of Missouri engineers are one step closer to painless fillings. In less than a minute , the plasma brush disinfects and clean out cavities for fillings. In Continue Reading
