A Popular Science Article on Tissue Engineering
From the Australian: "Generating new body organs in the lab is the stuff of Hollywood fantasy. But judging by the latest experimental findings, science fiction may soon be science fact. ... Already, Continue Reading
Mitochondrial Antioxidants Fail in Flies
Mitochondrially targeted antioxidants - such as gene engineering of increased amounts of catalase - are shown to extend life in mice, but here researchers find no such effect (or a negative effect) Continue Reading
A Summary of the CALERIE Study
CALERIE is the largest present study of calorie restriction in humans: "In a robust and consistent manner, sustained caloric restriction (CR) has been shown to retard the aging process in a variety Continue Reading
Branched-Chain Amino Acids and Mouse Life Span
Inevitably, researchers who focus on slowing aging through metabolic manipulation will uncover ingested compounds that alter metabolism in beneficial ways, and thus very modestly raise life Continue Reading
Lifestyle Choices Matter
A brief summary of recent research into risk factors for disease and human longevity: "A set of currently known alleles increasing the risk for coronary artery disease, cancer, and type 2 diabetes as Continue Reading
Thoughts on Protein Turnover and Longevity
Your cells are constantly creating and destroying the protein components of their machinery. All of the known metabolic alterations that enhance longevity affect these processes in some way: Continue Reading
Historical Inheritance of Life Span
Looking back at historical data on life span in human lineages, researchers find the result you might expect from centenarian studies - the most long-lived families tend to have more long-lived Continue Reading
Longevity Meme Newsletter, October 11 2010
LONGEVITY MEME NEWSLETTEROctober 11 2010The Longevity Meme Newsletter is a weekly email containing news, opinions, and happenings for people interested in aging science and engineered longevity: Continue Reading
Revisiting the Free Radical Theory of Aging
Thoughts on the impact of better technology on free radical theory: "The role of oxidative stress in aging proposed by the free radical theory has been the focus of investigations for more than fifty Continue Reading
Early Development, Moose, and Later Arthritis
From the New York Times: "In the 100 years since the first moose swam into Lake Superior and set up shop on an island, they have mostly minded their moosely business, munching balsam fir and trying Continue Reading
Investigating the Aging of Stem Cells
From the Korea Times: "Stem cells, or early-stage cells that retain the potential to turn into other specialized types of cells, are intriguing for their immense potential in treating a wide range of Continue Reading
What We Know About Fat Tissue and Longevity
In a nutshell: "Adipose tissue accounts for approximately 20% (lean) to 50% (in extreme obesity) of body mass and is biologically active through its secretion of numerous peptides and release and Continue Reading
Longevity Meme Newsletter, August 16 2010
LONGEVITY MEME NEWSLETTERAugust 16 2010The Longevity Meme Newsletter is a weekly email containing news, opinions, and happenings for people interested in aging science and engineered longevity: Continue Reading
Aging, Inflammation, and Osteoarthritis
Low-level chronic inflammation is produced by the aging immune system and causes many further problems: "Osteoarthritis (OA) is the most common cause of chronic disability in older adults. Although Continue Reading
Exercise Versus Calorie Restriction
The differences in a nutshell: "Calorie restriction (CR) is the only paradigm that has consistently increased lifespan in a wide variety of model organisms. Many hypotheses have been proposed as the Continue Reading
Stem Cell Therapies for Animals Further Ahead
While the FDA tries to block commercial application of stem cell therapies in the US, veterinary practices continue to demonstrate that the technology is ready and potentially useful: "A Golden Continue Reading
Stem Cells Versus Acute Lung Injury
Via ScienceDaily, an example of the sometimes indirect way in which stem cell transplants can cause benefits: "Acute lung injury is brought on by a number of conditions, such as pneumonia and sepsis, Continue Reading
Guiding the Next Generation of Researchers
We'd like to see the research community persuaded to work on the Strategies for Engineered Negligible Senescence rather than focusing on merely slowing aging via traditional drug development. So Continue Reading
Aggregates are Universal in Aging
Via EurekAlert! a reminder that we can think of most age-related conditions as resulting from one or more forms of damage that everyone suffers to some degree - but has progressed further in those Continue Reading
More Evidence for the Costs of Visceral Fat
Don't become fat: "Individuals with a large waist circumference appear to have a greater risk of dying from any cause over a nine-year period ... Having a large waist circumference has previously Continue Reading
