Lessons From the Mouse
A reminder of the role of the laboratory mouse in aging research: "Aging, which affects all organ systems, is one of the most complex phenotypes. Recent discoveries in long-lived mutant mice have Continue Reading
Aging of the Innate Immune System
The innate immune system declines with age, just like the adaptive immune system. The details are different: "The innate immune system is composed of a network of cells including neutrophils, NK and Continue Reading
Stayin’ Alive: That’s What Friends Are For
Relationships improve your odds of survival by 50 percent. Continue Reading
Fight These 4 Causes of Aging
Think you can't control how quickly you age? Think again, says nutritionist and author Jonny Bowden. Continue Reading
Polyphenols Found in Green Tea Can Help Save Diabetics
Polyphenols or phytochemicals found in green tea can help fight off bad cholesterol and harmful sugar-derived substances through strong antioxidant activity in the body. In a recent scientific Continue Reading
Resveratrol A Potent Weapon Against Prostate Cancer
Resveratrol may be helpful in reducing the growth of prostate cancer cells and also provides a myriad of other health benefits. According to the US Agricultural Research Service, the compound Continue Reading
Save Your Brain With Vitamin E and Vitamin D
Not having enough natural vitamin E and naturally-produced vitamin D in the body can predispose a person to dementia and cognitive decline. In a recent Dutch study published in the Journal of Continue Reading
Harnessing Hormesis
Hormesis is here examined in the context of exploiting it to slow aging: "The process of aging is accompanied by a progressive reduction of biological dynamical sophistication, resulting in an Continue Reading
An Example of Early Life Damage Affecting Longevity
Per the reliability theory of aging, we should expect to see shorter life expectancies result from damage or stress in early life. Here, a historical analysis supports that line of thinking: Continue Reading
Considering Cryonics and Neuronal Survival
From Depressed Metabolism: "The debilitating effects of a stroke are the result of the (delayed) neuronal death that follows an ischemic insult to the brain. In cryonics, biochemical or freezing Continue Reading
Social Connectivity and Mortality Risk
This study crunches the numbers to show that being socially connected has an effect on life expectancy comparable to that of exercise. Why this correlation exists is still up for debate, but it is Continue Reading
Exercise: Good at Any Age
Failing to exercise damages your prospects for healthy life in the future: "one in three men and one in two women over the age of 75 are not physically active at all. A recent study led by the Continue Reading
Lysosomal Dysfunction and Alzheimer’s Disease
Your lysosomes are recycling units, but their function slowly fails with age - meaning your cells degrade as they fill with waste and junk. More rapid and selective lysosomal failure in brain cells Continue Reading
Why Pay Attention to Accelerated Aging Studies?
In a nutshell, this is why research into so-called accelerated aging conditions may be relevant to longevity science: "One of the many debated topics in ageing research is whether progeroid syndromes Continue Reading
MDR Proteins and Cellular Longevity
An interesting study that provides another view of the relationship between accumulating damage, repair systems, and life span in cells: "Yeast cells, much like our own cells, have a finite ability Continue Reading
Methuselah Foundation Newsletter, July 2010
The latest Methuselah Foundation newsletter is out: "2010: Where We Are Now: Methuselah Foundation took on a big challenge: extending healthy human life. From SENS to My Bridge 4 Life, we've Continue Reading
More on the FDA and Aging as a Disease
From ShrinkWrapped: "If a physical change affects half of all people as they age, this would seem to suggest that it is a normal variant of human aging, which to the best of our knowledge is an Continue Reading
Envisioning Regrowth of Organs
From CBC News: "Scientists in Toronto are trying to crack the secrets of regeneration to trigger the human body to grow tissues and organs damaged by disease. In his lab at Mount Sinai Hospital, Dr. Continue Reading
Contemplating the Olm
From LiveScience: "Blind salamanders once thought to be baby dragons can live at least as long as most people, scientists now find. Adults of this species live nearly 69 years on average, with a Continue Reading
Calorie Restriction, Mitochondria, and Hormesis
A recent paper points to mitochondrially induced hormesis as a root cause of increased longevity with reduced calorie intake - which meshes well with the role of autophagy in this process. It Continue Reading
