SNAI2 as a Novel Radioprotector of Normal Tissue by Gene Transfer Using a Lentiviral Bicistronic SIN Vector.
In this study using a bicistronic lentiviral vector, we were able to provide proof of principle that lentiviral overexpression of SNAI2 might be used for radioprotective gene therapy to widen the Continue Reading
Penn Veterinary Researchers Say Gene Therapy Sets Stage For New Treatments For Inherited Blindness
In this study, the viral vector, or missile that carries the genetic material designed to correct a DNA mutation, was not intended to treat a disease but to demonstrate through the use of a Continue Reading
Researchers identify new genetic link to systemic scleroderma
An international research consortium including scientists from The University of Texas Health Science Center at Houston (UTHealth) has identified a new genetic link to the systemic form of Continue Reading
Scientists Find Cause of Involuntary Mirror Movements
Gene mutation impacts how the brain communicates with limbs, researcher says Source: HealthDay Related MedlinePlus Pages: Genes and Gene Therapy, Movement Disorders (Source: MedlinePlus Health News) Continue Reading
Severe Morning Sickness Passed from Moms to Daughters
Debilitating condition can sometimes require hospitalization, experts point out Source: HealthDay Related MedlinePlus Pages: Genes and Gene Therapy, Nausea and Vomiting, Pregnancy (Source: Continue Reading
Terry Dickson: ‘Bubba Gene, bless your heart’
In trying to plant his tomatoes upside down, Terry Dickson ended up with his shirt and shoes full of dirt. We offer instead this insightful correspondence from Bubba Gene Hightower, mayor of Pond Continue Reading
Gene therapy sets stage for new treatments for inherited blindness, researchers say
Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step Continue Reading
Gene Therapy Sets Stage For New Treatments For Inherited Blindness
Image Caption: This is a canine retina, injected with an AAV2/5 carrying the GRK1 promoter and the GFP gene. A red antibody that specifically identifies cones was used to label this class of Continue Reading
Ets-1 promotes the progression of cerebral aneurysm by inducing the expression of MCP-1 in vascular smooth muscle cells
Authors: T Aoki, H Kataoka, M Nishimura, R Ishibashi, R Morishita & S Miyamoto (Source: Gene Therapy) Continue Reading
Ex vivo culture of chimeric antigen receptor T cells generates functional CD8+ T cells with effector and central memory-like phenotype
Ex vivo culture of chimeric antigen receptor T cells generates functional CD8+ T cells with effector and central memory-like phenotype Gene Therapy advance online publication, April 29, 2010. Continue Reading
Electroporation- and mechanical ventilation-mediated gene transfer to the lung
Authors: C D Kaufman, R C Geiger & D A Dean (Source: Gene Therapy) Continue Reading
rAAV2/5 gene-targeting to rods:dose-dependent efficiency and complications associated with different promoters
rAAV2/5 gene-targeting to rods:dose-dependent efficiency and complications associated with different promoters Gene Therapy advance online publication, April 29, 2010. Continue Reading
Large animal models of hematopoietic stem cell gene therapy
Authors: G D Trobridge & H-P Kiem (Source: Gene Therapy)MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of Continue Reading
Mass spectrometry measurement of a therapeutic peptide for use in multiple sclerosis
Authors: J M Dadgari, R E Moore, K A Louie, T D Lee & M McMillan (Source: Gene Therapy) Continue Reading
Gene therapy sets stage for new treatments for inherited blindness, Penn veterinary researchers say
(University of Pennsylvania) Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina Continue Reading
Adipose-Derived Mesenchymal Stem Cells as Stable Source of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Delivery for Cancer Therapy
Findings describe a novel cell-based technology for delivery of a proapoptotic cancer gene therapy. (Source: Cancer Research) Continue Reading
Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles
Findings describe a biodegradable gene therapy nanotechnology that can silence genes more stably. (Source: Cancer Research) Continue Reading
Ceregene Has Initiated A New Phase 1/2 Trial Of CERE-120 For Parkinson’s Disease
Ceregene, Inc., a biopharmaceutical company, announced that enrollment is proceeding in a new Phase 1/2 clinical study evaluating CERE-120, a gene therapy product which delivers the neurotrophic Continue Reading
Study uncovers transcription control mechanism that is regulated by cancer-causing gene
A comprehensive new gene expression study in embryonic stem cells has uncovered a transcription control mechanism that is not only more pervasive than once thought but is also heavily regulated by Continue Reading
Gene That Could Grow a New Head ID’d
Could a Planarian flatworm’s ability to regenerate any part of its body -- including its head and brain -- be a major step toward regeneration therapy for humans? Continue Reading
