Development of Adoptive Cell Therapy for Cancer: A Clinical Perspective
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)MedWorm Message: Register forMedMatcha, MedWorm's medical advertising network, and receive $5 free advertising. Continue Reading
Antigen quality determines the efficiency of antitumor immune responses generated in the absence of regulatory T cells
Authors: A-S Bergot, A Durgeau, B Levacher, B M Colombo, J L Cohen & D Klatzmann (Source: Cancer Gene Therapy) Continue Reading
Knockdown of Efp by DNA-modified small interfering RNA inhibits breast cancer cell proliferation and in vivo tumor growth
Authors: K Ueyama, K Ikeda, W Sato, N Nakasato, K Horie-Inoue, S Takeda & S Inoue (Source: Cancer Gene Therapy) Continue Reading
MicroRNA and drug resistance
Authors: J Ma, C Dong & C Ji (Source: Cancer Gene Therapy) Continue Reading
Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene
Authors: C-K Tai, W Wang, Y-H Lai, C R Logg, W B Parker, Y-F Li, J S Hong, E J Sorscher, T C Chen & N Kasahara (Source: Cancer Gene Therapy)MedWorm Message: Register forMedMatcha, Continue Reading
Adenovirus infection results in alterations of insulin signaling and glucose homeostasis
Recombinant adenovirus (Ad) vectors can initiate an inflammatory response, limiting its use in gene therapy and basic research. Despite increased efforts to better understand Ad infection, little is Continue Reading
Could gene therapy be the future for muscular dystrophy?
Therapy , May 2010, Vol. 7, No. 3, Pages 287-290. (Source: Future Medicine: Therapy) Continue Reading
Genetic Pattern May Predict Leukemia Relapse
Children could be screened, treated more aggressively if deemed at risk, researchers say Source: HealthDay Related MedlinePlus Pages: Genes and Gene Therapy, Leukemia, Childhood (Source: MedlinePlus Continue Reading
Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B-cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells
Gene transfer vectors based on retroviruses are commonly used in gene therapy applications because of their unique ability to integrate efficiently into host genomes. This ability also forms the Continue Reading
New Tourette syndrome therapy considered
NEW HAVEN, Conn., May 13 (UPI) -- A U.S. study has identified a rare genetic mutation that researchers say suggests a potentially novel approach for treatment of tics and Tourette syndrome. Continue Reading
DNA electrotransfer to the skin: a highly translatable approach to treat peripheral artery disease
Gene Therapy advance online publication, May 13, 2010. doi:10.1038/gt.2010.68 Author: D Dean (Source: Gene Therapy) Continue Reading
Ectopic matrix metalloproteinase-9 expression in human brain tumor cells enhances oncolytic HSV vector infection
Authors: C-S Hong, W Fellows, A Niranjan, S Alber, S Watkins, J B Cohen, J C Glorioso & P Grandi (Source: Gene Therapy) Continue Reading
Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair
Authors: M L Hirsch, L Green, M H Porteus & R J Samulski (Source: Gene Therapy) Continue Reading
A combinatorial approach for targeted delivery using small molecules and reversible masking to bypass nonspecific uptake in vivo
Authors: Q Shi, A T Nguyen, Y Angell, D Deng, C-R Na, K Burgess, D D Roberts, F C Brunicardi & N S Templeton (Source: Gene Therapy) Continue Reading
Gene doping detection: evaluation of approach for direct detection of gene transfer using erythropoietin as a model system
Authors: A Baoutina, T Coldham, G S Bains & K R Emslie (Source: Gene Therapy)MedWorm Message: Register forMedMatcha, MedWorm's medical advertising network, and receive $5 free Continue Reading
Key Clinical Data Regarding Jennerex’s JX-594 to be Featured at American Society of Gene and Cell Therapy Meeting
Jennerex, Inc., a clinical-stage cancer biotherapeutics company, today announced that key data from its JX-594 intravenous administration Phase 1 dose escalation clinical study will be presented at Continue Reading
Quantitative fine-tuning of photoreceptor cis-regulatory elements through affinity modulation of transcription factor binding sites
Authors: J Lee, C A Myers, N Williams, M Abdelaziz & J C Corbo (Source: Gene Therapy) Continue Reading
Efficient inhibition of B-cell lymphoma xenografts with a novel recombinant fusion protein: anti-CD20Fab-LDM
Authors: C Xin, S Ye, Y Ming, Z Shenghua, M Qingfang, G Hongxing, S Xu, X Yuanfu, Z Yuan, F Dongmei, L Juanni, G Yingdai, J Lianfang, S Rongguang, Z Zhenping, W Jianxiang, C Tao, Y Chunzheng, X Continue Reading
Delivery of an EBV episome by a self-circularizing helper-dependent adenovirus: long-term transgene expression in immunocompetent mice
Authors: J S Gil, S D Gallaher & A J Berk (Source: Gene Therapy) Continue Reading
Increased interstitial pressure improves nucleic acid delivery to skin enabling a comparative analysis of constitutive promoters
Authors: E González-González, H Ra, R Spitler, R P Hickerson, C H Contag & R L Kaspar (Source: Gene Therapy) Continue Reading
