Viral Gene Therapy For The Future
Brain-tumor cells that are infected with a cancer-killing virus release a protein "alarm bell" that warns other tumor cells of the impending infection and enables them to mount a defense against the Continue Reading
Polyethylenimine as a Promising Vector for Targeted siRNA Delivery.
Authors: Nimesh S Abstract Recent discovery of RNA interference (RNAi) technology for gene therapy has triggered explosive research efforts towards development of small interfering RNA Continue Reading
Transcript characteristic of myostatin in sheep fibroblasts
AbstractMyostatin, a secreted growth factor highly expressed in skeletal muscle, negatively regulates skeletal muscle growth and differentiation. Recently, myostatin is emerged as a potential target Continue Reading
Elastin overexpression by cell?based gene therapy preserves matrix and prevents cardiac dilation
AbstractAfter a myocardial infarction, thinning and expansion of the fibrotic scar contribute to progressive heart failure. The loss of elastin is a major contributor to adverse extracellular matrix Continue Reading
Tissue Engineering and Regenerative Medicine – Where do we stand?
This article is intended to give an overview over some of the most recent developments and possible applications in RM through the perspective of TE achievements and cellular research. The synthesis Continue Reading
AAV?delivered polycistronic microRNA?clusters for knockdown of VEGF in vivo
ConclusionsWe have developed miRNA clusters encoding anti?VEGF effectors and shown in a mouse model that VEGF is efficiently down?regulated by scAAV2/8?delivered miRNA clusters, allowing potent Continue Reading
New Data Suggests Results of PLATO Genetic Sub-Study Outcomes for BRILINTA® (Ticagrelor) Not Driven by Poor …
AstraZeneca today announced results from a sub-analysis of the PLATO genetic sub-study that evaluated the impact of poor metabolizers of clopidogrel. Data suggests results were consistent with the Continue Reading
AUDIO: 'Exciting' new cystic fibrosis therapy
Imperial College's Professor Eric Alton explains new clinical trials of a new gene therapy treatment for Cystic Continue Reading
Percutaneous methods of vector delivery in preclinical models
Authors: D Ladage, K Ishikawa, L Tilemann, J Müller-Ehmsen & Y Kawase (Source: Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
Prevention of hepatocellular adenoma and correction of metabolic abnormalities in murine glycogen storage disease type Ia by gene therapy
Conclusion: These results confirm that AAV?GPE?mediated gene transfer corrects hepatic G6Pase?? deficiency in murine GSD?Ia and prevents chronic HCA formation. (HEPATOLOGY 2012.) (Source: Continue Reading
New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer
A summit on cellular therapy for cancer discussed and presented advances related to the use of adoptive cellular therapy for melanoma and other cancers. The summit revealed that this field is Continue Reading
Combination treatment in mice shows promise for fatal neurological disorder in kids
(Washington University School of Medicine) There are no effective treatments for Batten disease, a rare but fatal neurological disorder in children. But working in mice with the infantile form of the Continue Reading
Cancer cells send out the alarm on tumor-killing virus
(Ohio State University Medical Center) Brain-tumor cells that are infected with a cancer-killing virus release a protein "alarm bell" that warns other tumor cells of the impending infection and Continue Reading
Completed Clinical Trial Further Indicates Cell-in-a-Box(R) Encapsulation Technology Has the Potential to Treat a Wide Array of Solid Tumors
Cell-in-a-Box® Technology Enables Active Chemotherapy Drug to be Localized to Tumor Region SILVER SPRING, Md.--(Healthcare Sales & Marketing Network)--Nuvilex, Inc. (OTCQB:NVLX), an emerging Continue Reading
Controversies in HIV cure research
DiscussionMost efforts to date, including pharmaco, immuno or gene therapy, have failed to cure patients, with the notable exception of a stem cell transplant recipient commonly known as the Berlin Continue Reading
Cystic fibrosis gene therapy programme gets green light with public funding
A groundbreaking gene therapy trial for cystic fibrosis (CF) will begin in March, thanks to a new grant from a government funding body - News release (Source: Imperial College Continue Reading
AUDIO: ‘Exciting’ new cystic fibrosis therapy
Imperial College's Professor Eric Alton explains new clinical trials of a new gene therapy treatment for Cystic Fibrosis. (Source: BBC News | Health | UK Continue Reading
Gene Therapy Approaches For Lysosomal Storage Disorders, A Good Model For The Treatment Of Mendelian Diseases
Conclusions:? Lysosomal Storage Disorders represent a good model of study of gene therapeutic procedures which are, or could be, relevant to the treatment of several other mendelian diseases.© 2012 Continue Reading
Global Genetic Engineering Industry
NEW YORK, March 5, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Global Genetic Engineering Industry Continue Reading
Genetic Makeup of Tumors More Complex Than Thought
A small study that shows a surprising complexity of genetic changes within a single tumor has far-reaching implications for the march toward personalized cancer therapy, according to Continue Reading
