Improving TCR Gene Therapy for Treatment of Haematological Malignancies
Adoptive immunotherapy using TCR gene modified T cells may allow separation of beneficial Graft versus tumour responses from harmful GvHD. Improvements to this include methods to generate high Continue Reading
Decreasing Disease Severity in Symptomatic, Smn?/?;SMN2+/+, Spinal Muscular Atrophy Mice Following scAAV9-SMN Delivery
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
Long-Term Expression of Human Coagulation Factor VIII in a Tolerant Mouse Model Using the ?C31 Integrase System
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
Gene Therapy for Retinitis Pigmentosa Caused by MFRP Mutations: Human Phenotype and Preliminary Proof of Concept
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
Characterization of an HIV-Targeted Transcriptional Gene-Silencing RNA in Primary Cells
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
Genes May Give Clues to Severe form of Lupus
A DNA sequence known as an 'accelerator' might explain some aggressive cases, researchers say Source: HealthDay Related MedlinePlus Pages: Genes and Gene Therapy, Lupus (Source: MedlinePlus Health Continue Reading
Genes May Guide Intelligence Throughout Life
Some people stay smart as they age in part because of genetic factors, study suggests Source: HealthDay Related MedlinePlus Page: Genes and Gene Therapy (Source: MedlinePlus Health Continue Reading
Study Maps Path from Smoking to Emphysema in Mice
Immune response to smoke causes the disease, researchers say Source: HealthDay Related MedlinePlus Pages: Genes and Gene Therapy, Smoking (Source: MedlinePlus Health Continue Reading
Infusing CD19-Directed T Cells to Augment Disease Control in Patients Undergoing Autologous Hematopoietic Stem-Cell Transplantation for Advanced B-Lymphoid Malignancies
Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
Rapid titration of retroviral vectors using a ?-lactamase protein fragment complementation assay
Rapid titration of retroviral vectors using a β-lactamase protein fragment complementation assay Gene Therapy advance online publication, January 19, 2012. doi:10.1038/gt.2011.212 Authors: Continue Reading
Minicircle DNA electrotransfer for efficient tissue-targeted gene delivery
Authors: S Chabot, J Orio, M Schmeer, M Schleef, M Golzio & J Teissié (Source: Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
BRCA1 gene therapy reduces systemic inflammatory response and multiple organ failure and improves survival in experimental sepsis
Authors: H Teoh, A Quan, A K Creighton, K W Annie Bang, K K Singh, P C Shukla, N Gupta, Y Pan, F Lovren, H Leong-Poi, M Al-Omran & S Verma (Source: Gene Continue Reading
Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs
Authors: B L Ellis, M L Hirsch, S N Porter, R J Samulski & M H Porteus (Source: Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml Continue Reading
CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo
The costimulatory effects of CD27 on T lymphocyte effector function and memory formation has been confined to evaluations in mouse models, in vitro human cell culture systems, and clinical Continue Reading
Sendai virus vector?mediated brain?derived neurotrophic factor expression ameliorates memory deficits and synaptic degeneration in a transgenic mouse model of Alzheimer’s disease
AbstractGrowing evidence suggests that decreased brain?derived neurotrophic factor (BDNF) levels are associated with Alzheimer's disease (AD) pathogenesis. Therefore, BDNF gene therapy is considered Continue Reading
How Has Stephen Hawking Lived to 70 with ALS?
Stephen Hawking turns 70 on Sunday, beating the odds of a daunting diagnosis by nearly half a century. Source:http://rss.sciam.com/sciam/topic/gene-therapy Continue Reading
Baby Monkeys with 6 Genomes Are Scientific First
They look like ordinary baby rhesus macaques , but Hex, Roku and Chimero are the world's first chimeric monkeys, each with cells from the genomes of as many as six rhesus monkeys. Continue Reading
Genetic composition of multicentric lung tumors appears to be similar
Multicentric carcinogenesis with the same genetic mutation appears to occur in lung adenocarcinoma, according to data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Continue Reading
First details of genetic alterations that fuel early T-cell precursor ALL
Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a Continue Reading
Global Genetic Testing Market Analysis
NEW YORK , Jan. 11, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Global Genetic Testing Market Analysis Continue Reading
