Amniotic Membrane Used to Repair Cartilage

A novel methodology in : “The objective was to evaluate the utility of cryo-preserved human (HAM) as a support for repairing human injuries, which have a very limited capacity for self-healing … The results [show] that cryo-preserved HAM is useful as a scaffold for growing human in cell therapy and for repairing human cartilage injuries. … It provides a more regular surface and fills in the cavities and fissures … The authors cultivated the chondrocytes (cells that form part of the cartilaginous tissue), isolated from human articular cartilage, on the amniotic membrane over a period of three and four weeks. The amniotic membranes were used to develop 44 repair models of arthritic human articular cartilage , which was assessed between four and 16 weeks later. The HAM also bonds well with the native cartilage. … In some models, we could not differentiate between where the native tissue stopped and the neo-synthesised tissue began. … This tissue had a fibrous appearance and high cellular density (cellularity), which in some cases was greater than that of the actual native cartilage.”

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(1) regenerative medicine
URL: http://www.longevitymeme.org/topics/stem_cells_and_regenerative_medicine.cfm
(2) amniotic membrane
URL: http://en.wikipedia.org/wiki/Amniotic_membrane
(3) articular cartilage
URL: http://en.wikipedia.org/wiki/Articular_cartilage
(4) chondrocytes
URL: http://en.wikipedia.org/wiki/Chondrocyte
(5) in vitro
URL: http://en.wikipedia.org/wiki/In_vitro
(6) http://www.eurekalert.org/pub_releases/2010-06/f-sf-amu062310.php
URL: http://www.eurekalert.org/pub_releases/2010-06/f-sf-amu062310.php
(7)
URL: http://www.longevitymeme.org/news

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